The Herman B Wells Center for Pediatric Research conducts basic science and translational research as a Division within the Department of Pediatrics at the Indiana University School of Medicine, offering exceptional opportunities for collaborations between basic scientists and physicians. The goals of the Wells Center are to increase knowledge of the causes and mechanisms of serious pediatric diseases, to develop innovative approaches to diagnosis and treatment of childhood diseases, and to provide an outstanding training environment for medical and graduate students, residents, and fellows. Work in the Wells Center focuses on both discovery basic research and "translational" studies, which seek to rapidly move basic or bench research findings into the clinical setting. The research programs of Wells faculty are multidisciplinary and traverse traditional clinical section boundaries. Seven programs constitute the working groups within the Wells Center and include: Asthma and Allergic Diseases, Basic Diabetes Research, Cardiovascular Genetics, Developmental Cardiology, Hematologic Malignancies and Stem Cells, Infectious Diseases and Global Health, and Molecular Oncology and Experimental Therapeutics. Most Wells Center faculty members hold secondary faculty positions in the Indiana University School of Medicine Basic Science Departments. Wells Center research programs have achieved national recognition and continue to expand. The research endeavors of the faculty have led to an outstanding record for attaining peer-reviewed, external research funding, including support from numerous Institutes (NCI, NHLBI, NIAID, NICHD, NIDDK, NIGMS) of the National Institutes of Health (NIH), the American Heart Association, the American Cancer Society, the Juvenile Diabetes Research Foundation, and the Department of Defense.