Research in Clinical Pediatrics and Behavior

Fortenberry, J. Dennis, MD, MS in epidemiology (Adolescent Medicine, Pediatrics)
He has extensive background in theoretical and empirical approaches to sexual behavior research with adolescents, having trained with Richard Jessor, PhD, University of Colorado. His research program over the past 15 years has addressed the multiple factors associated with sexual behavior and sexually transmitted diseases among adolescents. Included are: the importance influences of peers and family and contextual and interpersonal factors; the role of sexual partners as sources of social support on adolescent care seeking for STDs; stigma and low health literacy as important barriers to appropriate health; and interpersonal relationship factors as important predictors of sexual and contraceptive behaviors.

Lemons, James, MD, (Neonatology, Pediatrics)
The primary focus of his research program currently is the performance of randomized clinical trials in the newborn intensive care population. This is largely accomplished through large multicenter trials, funded by NICHD, designed to evaluate new interventions or treatments in this patient population. In addition fellows in training and faculty within the Section of Neonatal-Perinatal Medicine have actively participated as investigators or principal investigators of trials within the NICHD Neonatal Research Network. Further, many ancillary studies are performed within the large trials, focused on the research expertise of the faculty. He is intent on expanding clinical investigations with necessary infrastructure into Kenya, where he has a collaborative relationship with a medical school.

Orr, Donald, MD (Adolescent Medicine, Pediatrics)
His research focuses on health-damaging and health protective behaviors that may place and adolescent at risk for poor health status. His group is currently studying the biological, behavioral and contextual factors related to risk for sexual behavior and sexually transmitted infections among middle adolescent women. Another project examines the impact (unintended pregnancy, incident sexually transmitted infections) of providing emergency contraception to women.

Rodriguez, Henry, MD, (Endocrinology & Diabetes, Pediatrics)
The focus of his clinical research relates to the prevention of diabetes. He is currently principal investigator of The NIH supported Diabetes Prevention Trial ? Type 1 (DPT-1), designed to determine if the clinical onset of Type 1 Diabetes can be delayed or prevented, and the Type 1 Diabetes Trial Net: Indiana University Clinic Center that screens individuals at risk for Type 1 Diabetes and investigates potential therapies to treat or prevent the diseases. The Prevention of Diabetes Progression Trial (PDPT) investigates the safety and efficacy of an IL-2 receptor antagonist, Daclizumab, in inducing selective immune suppression and in preventing complete β cell destruction in children newly diagnosed with Type 1 autoimmune diabetes.

Zimet, Gregory, PhD, (Adolescent Medicine & Psychiatry)
His research interests broadly involve the study of adolescent sexual and health behaviors related to STD prevention and screening. Over the past seven years, the major thrust of his research has involved examinations of the acceptability of STD/HIV immunization to adolescents, their parents, and health care providers. More recently, he has focused, as well, on the acceptability of screening tests for sexually transmitted infections and on the potential psychosocial burdens associated with unexpectedly testing positive for an STD. In developing these lines of research, he has acquired expertise in conjoint analytic techniques, which allow for the examination of how the characteristics of a product (e.g., an STD vaccine or screening test) influence acceptability.