EMPLOYMENT OPPORTUNITIES
The Wells Center for Pediatric Research, a highly supportive environment for interactive basic science and clinical research, is a fast-paced, cutting edge research facility, which offers a unique environment for training. The goal of research in the Wells Center is to improve the understanding and treatment of devastating diseases, which affect children.
Postdoctoral Fellowship Position
A post-doctoral position is available in a developmental hematopoiesis lab in the Wells Center for Pediatric Research, IUPUI. Candidates with experience in endothelial progenitor cell and/or cardiovascular biology, multi-color flow cytometric analysis, mammalian cell tissue culture and molecular biology are encouraged to apply. Experience in small animal handling and survival surgeries is required.
Interested individuals with a record of research productivity should submit their curriculum vitae, and the names of at least three references to: Dr. David Ingram (dingram@iupui.edu), Wells Center for Pediatric Research, 1044 W. Walnut, R4-470, Indianapolis, IN 46202.
Postdoctoral Fellowship in Cardiovascular Development, Indiana Univ. School of Med, Indianapolis, IN
Research in our laboratory is focused on multiple aspects of cardiovascular development; including the molecular regulation of lineage determination, transcription factors, congenital heart defects, regulation of endocardial cushion cell terminal differentiation and valve formation. This particular ßigH3 adhesion project will test the hypothesis that secreted Periostin and TGFß and/or BMP-dependent factors regulate cardiac valve ECM assembly in a TGFß fashion. Transgenic, gene targeting, gene profiling, cellular imaging, ultrastructural imaging, and proteomics core facilities are available on site. Candidates with experience in the areas of developmental biology, cell biology, molecular and/or vertebrate genetics are encouraged to apply. Additionally, it would be helpful if applicants have specific experience in one or more of the following techniques that will be required for this project: tissue/organ culture, establishment of permanent cell lines and/or ES cell differentiation; luciferase/EMSA/ChIP analysis; transgenic vector construction; and, in vitro/in vivo promoter analysis. Interested individuals with a record of research productivity should submit their curriculum vitae, and the names of at least three references to:
Simon J. Conway PhD,
Professor of Pediatrics (Cardiology),
Cardiovascular Development Group,
Herman B Wells Center for Pediatric Research,
Indiana University School of Medicine,
Indianapolis, IN 46202.
e-mail: siconway@iupui.edu
web: www.wellscenter.iupui.edu/conway.html
Postdoctoral Fellowship Position
A position is now open in the area of hematology and molecular oncology in the Molecular Oncology Group at the Herman B Wells Center for Pediatric Research, Department of Pediatrics, IU School of Medicine. The Molecular Oncology Group is composed of six laboratories that are all committed to collaborative and first-rate cancer research.
Research in our laboratory (www.wellscenter.iupui.edu/chun.html) is focused on multiple aspects of how cell cycle progression, differentiation, and survival are regulated. In particular, we are investigating how ubiquitin-mediated protein degradation and Cul4A ubiquitin ligases regulate these processes, and we are examining these functions in both hematopoietic and non-hematopoietic cells. Findings demonstrate numerous Cul4A ubiquitin ligases that differ in subunit composition and target specificity, so future studies are aimed at identifying and characterizing targets important for proliferation, differentiation, and apoptosis and the composition of their Cul4A ligases. We are using genetic and molecular approaches, including knockout and transgenic mice, cultured primary cells, cell lines, and in vitro enzymatic assays. Candidates with experience in the areas of vertebrate genetics, hematopoiesis, molecular biology, cancer biology, or protein biochemistry are encouraged to apply. Additionally, it would be helpful if applicants have specific experience in one or more of the following techniques that will be required for this project: culturing primary hematopoietic cells, hematopoietic cell assays, RNAi, tissue culture, proteomics, and protein interaction studies.
Interested individuals with a record of research productivity should submit their curriculum vitae, and the names of at least three references to:
Dr. Kristin T. Chun
Herman B Wells Center for Pediatric Research,
1044 W. Walnut
R4 474
Indianapolis, IN 46202.
e-mail: kchun@iupui.edu
web: www.wellscenter.iupui.edu/chun.html
Postdoctoral Fellowship Position
Research in our laboratory is focused on functional imaging of living specimens using linear and non-linear optical microscopy. This particular project will utilize two-photon laser scanning fluorescence microscopy to examine the potential of a variety of transplanted donor cell types (bone marrow stem cells, skeletal myoblasts, embryonic stem cell-derived cardiomyocytes, and cardiovascular progenitor cells) to functionally couple with the host myocardium following their transplantation into normal or injured hearts. Functional integration of engrafted, genetically tagged donor cells will be assessed via fluorescence-based measurements of changes in intracellular calcium and / or transmembrane voltage. Imaging experiments will be performed in the Indiana Center for Biological Microscopy (www.nephrology.iupui.edu/imaging/ ), a state-of-the-art facility equipped with multiple single- and dual-photon laser scanning microscopes. The project will also involve survival surgeries of small animals, flow cytometric analyses, mammalian cell culture, histology, cytology, immunochemistry of cells and tissue, and a variety of molecular biology techniques. Candidates with strong interest/experience in quantitative life imaging of cardiovascular specimens are encouraged to apply.
Interested individuals should submit their curriculum vitae, and the names of at least three references to:
Michael Rubart, MD
Assistant Professor of Pediatrics (Cardiology)
Riley Heart Research Center,
Herman B Wells Center for Pediatric Research,
Indiana University School of Medicine
1044 West Walnut Street, R4 W319
Indianapolis, IN 46202
e-mail: mrubartv@iupui.edu
web: www.heartresearch.iupui.edu/index.php?faculty=106
Postdoctoral Fellowship Positions
Salary commensurate with experience. Send CV, statement of research interests,
indicating lab(s) of interest, and 3 letters of recommendation to:
Leigh A. Crick, PHR
Manager of Human Resources and Administration
Wells Center for Pediatric Research
Cancer Research Institute
1044 W. Walnut, Room 402
Indianapolis, IN 46202email: lcrick@iupui.edu
phone: 317-278-0746
fax: 317-274-9906
PLEASE REFER TO THE IUPUI HUMAN RESOURCES WEB PAGE (http://www.hra.iupui.edu) FOR A CURRENT LISTING OF JOB OPPORTUNITIES AT THE WELLS CENTER.
Research Analysts I (PAE10)
Master’s Degree in science related field, or Bachelor’s degree
in science related field with 3 years of experience required. Salary
commensurate with experience. Interested applicants should apply through
the IUPUI Human Resources office by applying on-line.
Research Technician I (RS07)
Bachelor’s degree in science related field; or advanced college
science plus two years research experience; or college level science
plus two years laboratory experience and two years research experience;
or High School plus three years of laboratory experience and two
years of research experience. Salary commensurate with experience.
Interested applicants should apply through the IUPUI Human Resources
office by applying on-line at www.hra.iupui.edu.
The IUPUI Human Resources office is located in the Union Building, 620 Union Drive, Room 340 (telephone: 317-274-7617). A current list of openings is available at www.hra.iupui.edu.
Indiana University is an EED/AA
employer, M/F/D.
