Cardiac Development Biology

The Cardiac Development Biology Group is unique in terms of the number of independent investigators focused on cardiac development research and in terms of the interdisciplinary nature of their respective research programs. The group has grown steadily since its inception, and plans for future growth have been developed and has 6 research faculty and over 30 members, including basic and clinical post-doctoral fellows, Ph.D. and M.D./Ph.D. graduate students and technicians.

The Cardiac Development Biology Group utilizes a multidisciplinary approach to study the origins, etiology and treatment of heart failure in the young. As such, research focuses on how gene expression, cell survival and cell growth pathways are interrelated in the origins of heart failure in the young, and furthermore, how manipulation of these pathways can be utilized therapeutically. Together, the six investigators are a highly collaborative and successful research group, which is evidenced in the extramural funding (NIH, AHA, MOD, etc) received by the investigators individually and in collaboration with other investigators.

The investigators, in collaboration with the clinical faculty in Pediatric Cardiology, and the surgeons in Cardiovascular Surgery share a common interest in the development of translational research projects. Together, the research, medical and surgical teams combine to create a comprehensive program, integrating basic science, clinical and surgical missions towards a common focus in the etiology and treatment of heart failure in the young.